Southwest Mississippi Regional Medical Center is an integrated healthcare delivery network serving the residents of Southwest Mississippi and bordering Louisiana parishes. Founded in 1969, the main facility is located in McComb, Mississippi, and is licensed for 160 beds.
The medical center provides a comprehensive range of clinical services. These include acute care, cardiovascular care, cancer treatment, rehabilitation, and women's health services. Its emergency department is classified as a Level IV Trauma Center.
Several of these services are delivered through affiliated institutes and centers, including the Cardiovascular Institute of Mississippi, the Mississippi Cancer Institute, the Southwest Center for Rehabilitation, and the Southwest Regional Women's Center Maternity Suites.






