UChicago Argonne, LLC operates Argonne National Laboratory, a multidisciplinary research institution founded in 1946 and opened by the University of Chicago. Originally chartered as the nation's first laboratory for peaceful atomic energy research, it evolved from its origins in the Manhattan Project to become a broad-based scientific enterprise. The laboratory employs over 3,400 people and maintains significant capabilities across nuclear physics, energy storage, battery technology, climate science, computational discovery, and national security research.
The laboratory operates major user facilities including the Advanced Photon Source and the Argonne Leadership Computing Facility, which support scientific research across multiple disciplines. Its work spans energy security through battery development for electric vehicles and next-generation energy systems, climate science and environmental sustainability, computational and artificial intelligence applications to scientific discovery, and fundamental research in particle and matter physics with applications to medical advances.
Research priorities centre on developing solutions in energy storage, climate mitigation, national security, and computational discovery. The laboratory combines supercomputing capabilities with artificial intelligence to accelerate scientific breakthroughs. Its position as a major research institution reflects both its historical role in nuclear science and its contemporary focus on challenges in energy, climate, and technological innovation.